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Interestingly, promoting GSH synthesis with NAC treatment, which can affect early (NAPQI scavenging) and later events (scavenging of mitochondrial peroxynitrite) [32], attenuated necrotic cell death but did not induce secondary apoptosis [58]

In a case report, cytotoxic T-cell (CD8 + ) infiltration into the thyroid gland was observed in a patient with nivolumab-induced thyroid dysfunction, 25 suggesting the involvement of cellular immunity

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Glucagon-like peptide 1, insulin, sensory neurons, and diabetic neuropathy